Despite previously suffering a miscarriage, the E! News host revealed to UsMagazine.com that she and husband Bill Rancic are trying again for a baby via IVF.
"Sometimes I have to get [injections] 21 days in a row, three times a day," Giuliana told the mag. "It's a lot. But you've got to do it."
Though the treatments can take a toll on a person, Giuliana, 36, remains optimistic about her chances of conceiving again.
"The good news is that IVF did work as we did get pregnant," she said, referring to her miscarriage eight weeks into her first pregnancy in October.
Giuliana Rancic Pregnant
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