Canning questions Sheen on his controversial remarks and his public feud with the CBS comedy's creator, Chuck Lorre, which resulted in the hit show's suspension, as well as his notorious headline-making actions.
Portions of the interview will air on "Good Morning America" on Monday and Tuesday, and throughout ABC News platforms.
"Two and a Half Men" had been on hiatus since January after Sheen entered rehab. CBS announced Thursday night that it had canceled the rest of the season after the actor's scathing rant against Lorre on the radio program "Alex Jones Show."
In that interview, Sheen said of Lorre that he must have embarrassed him "in front of his children and the world by healing at a pace that his un-evolved mind cannot process."
Charlie Sheen Interview with ABC News
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