Skip to main content

Obscure Enzyme may Predict which Cancers will Spread

Obscure Enzyme may Predict which Cancers will Spread - In a new study published in the current issue of the Journal of Clinical Investigation, high levels of a protein called CPE-delta N accurately predicted 90 percent of the time whether a tumor moved on from its original site in patients with liver cancer or some rare forms of adrenal cancer.

"We can tell from the levels [of the protein] whether the tumor has spread, and we can predict whether the tumor is likely to recur in the same tumor or tissue or in other parts of the body," senior study author Y. Peng Loh, of the U.S. National Institute of Child Health and Human Development, said during a Thursday news conference on the finding. "Currently, there are no accurate biomarkers that can achieve such predictions."

Cancer that has spread, or metastasized, is often fatal, and scientists have long tried to find ways to predict whether metastasis is likely to occur, not only to help guide and individualize treatment, but also to provide targets for potential future therapies.

Although it's still early, the results suggest it may be possible to develop tests that assess the likelihood of a cancer spreading and to treat it before it does so, the researchers say.
Doctors now use the stage and grade of a tumor to determine a patient's prognosis, and in this study those factors were far less accurate than the protein.
One expert found the finding intriguing.

Obscure Enzyme may Predict which Cancers will Spread

Comments

Popular posts from this blog

Urban Meyer Stepping Down

Urban Meyer Stepping Down - Well, it appears as if it’s deja vu all over again.

Less than 12 months after retiring and then un-retiring, Urban Meyer is apparently stepping down as Florida’s head coach. There’s no word on if he will be stepping back up tomorrow.

Urban Meyer Stepping Down

According to Todd Wright of Sporting News radio, GatorUpdates.com and AOL Fanhouse‘s Brett McMurphy Meyer will announce at a 5 p.m. ET press conference Wednesday that he is resigning/retiring as the Gators’ head coach. There are no further details available at this time, other than GatorUpdates reporting over the weekend that Meyer checked into a hospital the week of the UGA game and has been undergoing tests since.

Obviously, we’ll have more on this story throughout the day and well into the night…

Urban Meyer Stepping Down

Matt Cassel Undergoes Appendectomy

Matt Cassel Undergoes Appendectomy - The mystery of Matt Cassel missing practice Wednesday coupled with the Kansas City Chiefs promoting quarterback Tyler Palko has been solved.

The team has announced that Cassel underwent an appendectomy on Wednesday morning. The Chiefs say they expect Cassel to return to work this week. Returning to work and being ready to perform well in the team’s biggest game of the season on Sunday against San Diego are two different things. ESPN’s Adam Schefter is reporting the Chiefs are viewing Cassel as being questionable to play in the game.

Clearly, this is terrible timing. The Chiefs are 8-4 and would take a major step toward the playoffs with a win over the Chargers. Cassel has played very well for the past two months. If he can’t play, the brittle Brodie Croyle would face the Chiefs in his first action of the season. Croyle last played in Week 13 of the 2009 season.

Matt Cassel Undergoes Appendectomy

Cassel’s availability will come down to whether he…

100-calorie Packs Diet

100-calorie Packs Diet - Did you know recent studies show chronic dieters tend to consume more calories when foods and packages are smaller? Consumer behavior was observed in the study regarding "mini-packs," 100-calorie food packages that are marketed to help people control calorie intake.

The study revealed that one group that over-consumes the mini-packs is chronic dieters - individuals making a conscious effort in trying to manage their weight and food intake.

This shows that the distorted perception of small packages may actually undermine dieters' attempts to limit calories.

Consider this: Consumers perceive the mini-packs to be a generous portion of food - numerous small food morsels in each pack and multiple mini-packs in each box - while on the other hand, consumers perceive the mini-packs to be diet food. For chronic dieters, this perceptual dilemma causes a tendency to overeat, due to their emotion-laden relationship with food.

In a series of focus group studi…